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Do not use Adipex-P if you are pregnant or breast-feeding a baby.

You should not take Adipex-P if you have a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, stroke), severe or uncontrolled high blood pressure, overactive thyroid, glaucoma, a history of pulmonary hypertension, if you are in an agitated state, or if you have a history of drug or alcohol abuse.

Do not use Adipex-P if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.